Pharmacology of Remdisivir
Remedisivir, an adenosine analogue, incorporates itself into viral RNA
chains resulting in pre-mature termination [3]. It has been
described as a potential antiviral medication against a broad variety of
RNA viruses, including SARS and MERS, in animal models [4,5] .
Remdisivir also inhibited virus infection in a human cell line that is
susceptible to SARS-CoV-2 [6]. Remdesivir has also been shown to
reduce viral load of MERS-CoV in the lung tissue of infected mice.
Moreover, it enhanced lung function and reduced damage to the lung
tissue. [7] Among the various therapeutic candidates, it showed
success both in vivo and in vitro against coronaviruses in general.
[8]