Statistical Analysis
Statistical analysis were performed using the Statistical Package for Social Sciences (SPSS) vs. 23 (IBM, Endicott, Broome_County, New York, United States). Numerical data were summarized using means and standard deviations; differences between groups were done using ANOVA or Kruskall-Wallis test. Categorical data were summarized as numbers and percentages, differences were analyzed with χ2 (chi square) test or fisher exact when appropriate. Receiver Operating Characteristics (ROC) analysis was performed to assess the performance characteristics of TMEM178 expression for asthma severity prediction. The best cutoff point and the corresponding sensitivity and specificity and Area Under the Curve (AUC) were analyzed. P <0.05 was considered significant.