Conclusion
Our study demonstrated the deterioration of 2DSTE-derived LA functions
along with the advanced grades of diastolic dysfunction. The decrease in
LA pump function in Grade 3 diastolic dysfunction is evident and it may
be associated with the extent of LA remodeling and fibrosis in these
patients. The strong correlation of the echocardiographic pulmonary
vascular resistance estimates with the LA strain parameters, and their
association with the diastolic dysfunction grades may inspire future
studies in HFpEF patients.