[insert Table 5 here]
The perfume formula obtained is shown in the second column of Table 6.
The maximum sensorial rating is 92.4. The new perfume consists of 3
fragrances in top note, 4 fragrances in middle note, and 3 fragrances in
base note. Their volume fractions vary in the range of 0.3-1.9% and the
total volume fraction of fragrances is 10.1%. Furthermore, this recipe
fulfills the four design targets. The \(LD_{50}\) and flash point are
6815 mg/kg and 15.1 °C, respectively. These are higher than their lowest
acceptable design targets (5000 mg/kg and 15 °C in Eq. 17-18). The
volume fractions of the 10 fragrances are less than their volume
solubility shown in Table S3. Thus, a homogeneous and transparent
perfume solution can be obtained. Figure 5a shows the odor profile
during the first 350 seconds. The intensity of benzyl acetate
(jasmine-like) and octyl acetate (apple-like) are 2.6 and 0.5,
respectively. The limonene with a lemon-like odor has the maximum
intensity of 2.8 after 5 minutes. Note that since the odor intensities
of other fragrances are much less than those of top note fragrances,
they are not shown in the figure. Figure 6a shows the simulated
diffusion profile of top note fragrances within 2 meters at 5 minutes.
Obviously, the maximum intensities are located at \(z=0\). The maximal
intensity of limonene can reach 33.5. As the distance increases, the
intensity decreases and down to zero beyond 2 meters. The simulated
diffusion profiles of 4 middle note fragrances at 1 hour and 3 base note
fragrances at 5 hours are illustrated in Figure S2a and S2b,
respectively.