Expression of cytokines in different genotypes of theIL2RA/rs2104286 locus
A decreased IL-10 level and an increased IL-17 cytokine secretion level were observed in the IL2RA /rs2104286 AA genotype individuals than in the AG genotype individuals (P <0.05), while there was no statistical difference in the TGF-β1 cytokine level (P >0.05). There was no significant difference in the IL-6 secretion levels among the IL2RA /rs2104286 AA, AG, and GG genotypes in anti-CD3 and anti-CD28 antibody-stimulated PBMC (P >0.05; Figure 3).