Expression of cytokines in different genotypes of theIL2RA/rs3118470 locus
For the rs3118470 locus, the homozygous TT genotype individuals had lower IL-10 and TGF-β1 levels and increased IL-17 level than the CC genotype (P <0.05). No significant difference was identified in the IL-6 level among the rs3118470 TT, CT, and CC genotype individuals in anti-CD3 and anti-CD28 antibody stimulated PBMCs (P >0.05, Figure 2).