Study design and setting
We constructed a prospective cohort of consecutive pregnant women with
confirmed SARS-CoV-2 infection (positive RT-PCR on nasopharyngeal swab)
who delivered in BCNatal (Hospital Clínic and Hospital Sant Joan de
Déu), Barcelona, Spain between March 13th and April
25th, 2020.
Clinical management and follow-up of these patients was made from
admission until hospital discharge according an established
protocol(14). Moderate or severe cases started
treatment for COVID with lopinavir/ritonavir, hydroxychloroquine and
azithromycin. Maternal monitoring during admission or labor included
hourly monitoring of blood pressure, heart rate, temperature,
respiratory rate and oxygen saturation. Labor was managed by attending
professionals adhering to personal protection equipment protocols, in a
dedicated delivery room under continuous fetal cardiotocographic
monitoring. The mode of delivery in women with COVID-19 with no criteria
of severe disease was guided by standard obstetric indications. After
hospital discharge, telephone follow-up was performed to detect
postpartum complications.