A 63 year old patient with chronic lymphocytosis and neutropenia is
described. A bone marrow biopsy showed a markedly hypercellular specimen
with an interstitial and intrasinusoidal lymphoid infiltrate.
Immunohistochemistry and immunophenotyping identified these as LGLs.
With paucity of erythropoiesis diagnosis of LGL leukemia with pure red
cell aplasia is reached.