Figure 2 . Patient 1: Bone marrow showing involvement by PTLD.
A. Bone marrow aspirate shows increased number of plasma cells (arrow)
and large B-cells (arrowhead) (A). Immunohistochemical studies highlight
both small and large B-cells (2B, CD20).
The abnormal clone (8 of 20 cells) exhibited loss of one X, and gain of
an extra chromosome 3 and a marker chromosome -
47,X,-X,+3,+mar[8]/46, XX[12]. Monosomy X has been reported in
the association with T-cell lymphoma 14.