While one of our main goals in this project was to use the mutant data from Cui et al to PETase variants that exhibit improved Tm, our all predictive models trained with this data set showed poor performance. We suspect that this poor performance can be attributed to two primary factors: first, the data set was considerably small, with only 85 mutant samples; second, many of the data represent mutations occurring towards the middle of the amino acid sequence, and likely do not adequately span the configuration space of possible mutations that we would be predicting for.