Figure 6 TRPA1 antagonist HC-030031 alleviates the symptoms of DNCB-induced AD mice. (A-C) Representative macroscopic features (A), ear thickness (B, only on day 20) and DNCB-induced spontaneous scratching behavior (C only on day 20) were evaluated on day 11 and 20 after treatment. (D, E) Representative H&E staining of (D) dorsal skin lesions and (E) the ear skin sections from groups of mice on the last day of the experiment (day 21) Scale bar, 100 μm; *p<0.05, **p<0.01