Fig.2 TRPA1 deficiency efficiently ameliorated the DNCB-induced AD-like symptoms. (A-C) Dermatitis score (A), ear thickness (B), and (C) DNCB-induced spontaneous scratching behavior wereevaluated on day 1 and at 3-day intervals from day 5 to day 20 (n=6). (D, E)Representative hematoxylin and eosin-stained of (D) dorsal skin lesions and (E) the ear skin sections on day 21. Scale bar, 100 μm; (E) Epidermis thickness was measured onhematoxylin and eosin-stained sections. (G) Ear thickness was determined on hematoxylin and eosin-stained sections. Data are presented as mean ± SEM of changes in values, *p<0.05, **p<0.01