Contributions:
UFR data collection and laboratory measurements, analyzed and interpreted data, manuscript draft
GP data collection, critical input to the manuscript
AJS data interpretation, manuscript draft and final version
JWF critical input to the manuscript
MA laboratory measurements, critical input to the manuscript
TZ critical input to the manuscript
CB study concept and design, critical input to the manuscript
HO study concept and design, study lead, data analysis and interpretation, manuscript draft and final version