Patient population
We systematically reviewed the available literature for ECGs of patients with diLQTS and subsequent TdP. We entered the MeSH term ‘drug induced long qt torsades de pointes’ into Medline and Embase and identified 1253 reports published until April 19th, 2020. Eligible articles had to include human subjects with available limb ECG leads with drug-induced QT interval prolongation and experiencing subsequent TdP. We also screened the references of eligible papers. After manual review, we identified 77 ECGs that were included in the current study. We also reviewed eligible ECGs with the same criteria from the hospital files of our institution (Hospital Haut-Leveque, University Hospital Bordeaux, Pessac, France) and furthermore included 7 patients.