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MACROLIDE-CLARITHROMYCIN TASK-FORCE FOR THE TREATMENT AND PROPHYLAXIS OF COVID-19 AS A SINGLE AGENT.
  • Eduardo Mansilla and 8 more.Orcid
Eduardo Mansilla and 8 more.
Orcid
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Peer review status:Published

Published in Pharmacology & Pharmacy volume 11 issue 06 on pages 85 to 104. 2020. 10.4236/pp.2020.116009

Abstract

SARS-CoV-2 is a novel RNA coronavirus responsible of a deadly pandemic: the clinical illness COVID-19. With only one authorized drug for emergency use in critically ill patients: Remdesivir, there is not any other approved drug or vaccine yet with proven potential to overcome this infection. We exposed here many scientific evidences to support our novel idea that a macrolide, basically Clarithromycin, could be effective as a single agent for treatment and prophylaxis of COVID-19. Clarithromycin could change the history of this pandemic. It could reduce the costs of treatment and the potential adverse effects when combining more than one drug such as with Hydroxychloroquine. Clarithromycin treatment and prophylaxis as a single agent could be much more simple, safe and cheaper as giving Chloroquine or Hydroxychloroquine alone or in combination with Azithromycin as well as other therapeutic options.