Methods
Study setting
This study was conducted at Fetal Medicine Unit of the Obstetrics and Gynecology Department at Royal Hospital. Royal Hospital is the only major tertiary Hospital, Muscat, the capital city of Sultanate of Oman. The institution provides multi specialist care and considered as an official referral center for congenital anomalies in Oman, as appointed by the Ministry of Health.
Pregnant women who followed at obstetric antenatal clinics had a routine anatomy scan between 18 -22 weeks of gestation, patients with high risk can be referred even earlier for first trimester scan, according to the obstetric history and condition. Women with antenatally diagnosed with major congenital anomalies had antenatal follow up with Fetal Medicine Unit. Most patients had two or more ultrasound examinations by fetal medicine senior consultants.