Study Study type Origin Total no. of patients Median Age (years) Proportion of hypertension Mortality Critical/Severe disease1
Adjusted Estimate Adjusted Estimate
Zhang et al [11] Retrospective, multicentre Hubei, China 1,128 ACEI/ARB=64 & Non-ACEI/ARB=64 100 HR=0.37 (0.15-0.89) HR= 0.32 (0.13-0.80)
Lee et al2 [12] Retrospective database review Korea 8,266 ACEI/ARB=67 & Non-ACEI/ARB=42 19.0 HR=1.07 (0.68-1.65) -
Yang et al [13] Retrospective, single centre Hubei, China 251 ACEI/ARB=65 & Non-ACEI/ARB=67 100 - -
Meng et al [14] Retrospective, single centre Shenzhen, China 42 ACEI/ARB=64 & Non-ACEI/ARB = 65 100 - -
Feng et al2 [15] Retrospective, multicentre China 65 ACEI/ARB=57 & Non-ACEI/ARB=63 14.5 - OR=0.41 (0.05-3.19)
Peng et al [16]
Retrospective, single centre
Wuhan, China
112
Mild= 62 & Severe=57.5
82.1
-
-
Chen et al2 [17] Retrospective, single centre Wuhan, China 123 Discharged=53 & Death=72 33.3 - -
Huang et al [18] Retrospective, single centre Wuhan, China 50 ACEI/ARB=53 & Non-ACEI/ARB=68 100 - -
Zeng et al2 [19] Retrospective, single centre Wuhan, China 274 ACEI/ARB=64 & Non-ACEI/ARB=69 27.3 - -
Li et al 20]
Retrospective, Single centre Wuhan, China
362
ACEI/ARB=65 & Non-ACEI/ARB=67
100
-
-
Liu et al [21] Retrospective, Multi centre China 78 ACEI/ARB>65 & Non-ACEI/ARB>65 100 -
Mehra et al [22]
Observational database
Asia, Europe and North America
8,910
ACEI/ARB & Non-ACEI/ARB= 49
26.3
OR= ACEI: 0.33 (0.20-0.54) ARB: 1.23 (0.87-1.74)
-
Ip et al2 [23] Retrospective, multicentre New Jersey, USA 1129 - 100 - -