Optimal centile Proportion (%) below cut off Proportion (%) below cut off AUC % Sensitivity % Sensitivity % Specificity % Specificity % PPV % PPV % NPV % NPV % Relative Risk Relative Risk 95% CI 95% CI
Overall cohort 11.3 16.0 62.3 62.3 62.3 36.8 36.8 84.1 84.1 1.0 1.0 99.7 99.7 3.1 3.1 2.9 - 3.2
Low Risk 15.2 15.5 61.3 61.3 61.3 35.1 35.1 84.6 84.6 0.8 0.8 99.7 99.7 2.9 2.9 2.8 - 3.2
High Risk 2.7 11.2 61.2 61.2 61.2 34.2 34.2 88.9 88.9 1.9 1.9 99.5 99.5 4.1 4.1 3.7 - 4.5
ROC, Receiver Operator Curve; AUC, Area Under Curve; CI, Confidence Interval; PPV, Positive Predictive Value; NPV, Negative Predictive Value. Values calculated according to respective cut-off point (optimal centile)