Insulin Autoimmune Syndrome (Hirata Disease): A Rare Case Report in an
Indian Patient Dr. Ratnesh Singh Kanwar (MBBS, MD), Dr. Himanshu Jaiswal
(MBBS, DRM Final Year Resident)
An unusual cause of spontaneous hypoglycemia is Insulin Autoimmune
Syndrome (IAS) or Hirata Disease, characterized by high levels of
insulinemia and circulating autoantibodies to insulin in subjects
without prior insulin administration.To the best of our knowledge, this
is the second case of IAS reported from India.