Figure 4. PEG-FGF2 conjugates promote the migration and
proliferation of HDFs in vitro. (A ) Cellular
proliferation activity of PEG-FGF2 conjugates was determined by CCK-8
assay using HDF cells. ***P < 0.001
vs. control group. Scale bar = 200 μm. (B, C ) Scratch wound
healing assay of HDFs in the indicated groups for 36 h. The red dotted
lines represent the wound boundary. Scale bar = 100 μm.*P < 0.05,***P < 0.001 vs. control group;##P < 0.01 vs. FGF2 group; n.s., no
significance. All data are displayed as means ± SEM of 5 independent
experiments.