Statistical Analysis
Statistical analysis was performed using Graphpad Prism 8.0 software (GraphPad, San Diego, CA). Data are presented as mean values ± SD. Each set of experiments was repeated independently at least three times with comparable results. Student’s t -tests were performed to determine the significance of differences between pairs. One-way analysis of variance (ANOVA) was utilized to determine significant differences between multiple groups. P <0.05 was considered statistically significant.