Abbreviations
FGF2: Fibroblast growth factor 2
PEG: Poly (ethylene) glycol
ERK1/2: Extracellular signal–regulated kinases 1 and 2
p-ERK1/2: phosphorylated ERK1/2
mPEG-MAL: monomethoxy PEG-maleimide
HDFs: Human dermal fibroblast cells
HUVECs: Human umbilical vein endothelial cells
CCK-8: cell counting kit-8
MMPs: metalloproteinases
HG: high glucose
H&E: Hematoxylin and Eosin
PCNA: Proliferating cell nuclear antigen