LIMITATIONS
This paper summarizes and analyzes the results of pathological
immunohistochemistry in patients with previous surgery, so the sample
size is small, and the detection of immunohistochemical indicators has
certain limitations, and a more comprehensive comparative analysis
cannot be undertaken. Postoperative adjuvant treatment was governed by
the patients’ consent, so there is no analysis of the combination of
immunohistochemical findings and the efficacy of clinical treatment. We
shall continue this line of study in subsequent more targeted research.
This paper only describes and analyzes the existing data, hoping to
provide ideas for the future in-depth study of head and neck mucosal
melanoma.
In conclusion, the analysis of local tumor markers will contribute to a
deeper understanding of the characteristics of mucosal melanoma. The
correlation between CD8 expression and PD-L1 expression in tumor tissue
also indicates the significance of effector T cell infiltration in the
tumor immune microenvironment and its role in the prognosis of patients,
but further research is required. We need to expand the sample size to
verify our conclusions on the incidence rate of lower head and neck
mucosa melanoma.
Conflicts of interest :There are no conflicts of interest to
report
Data Availability Statement :The data that support the
findings of this study are available on request from corresponding
author.