Rasagiline monoamine oxidase B (MAO-B) inhibitor: \cite{Statland2019}    2 mg/day rasagiline or placebo
Colchicine for Amyotrophic Lateral Sclerosis:      Colchicine 1 MG Oral Tablet or placebo

AMX0035 for Amyotrophic Lateral Sclerosis: 

MCI-186 in open label phase for Amyotrophic Lateral Sclerosis:  Double-Blind, Parallel-Group, Placebo-Controlled Manner MCI-186 \cite{2017}
Two ampoules (60 mg) of MCI-186 or placebo injection are intravenously administered once a day, for successive 14 days, followed by 14 days observation period (first cycle). Then treatment (10 days' administration during 14 days) - observation (14 days) cycle is repeated five times (2nd-6th cycles).
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