loading page

Are multiple sclerosis therapies safe in SARS-Cov-2 times?
  • +2
  • Francesco Ferrara,
  • Giovanni Granata,
  • Chiara Pelliccia,
  • Raffaele La Porta,
  • Antonio Vitiello
Francesco Ferrara
Azienda Unità Sanitaria Locale Umbria 1
Author Profile
Giovanni Granata
Local Health Authority Salerno
Author Profile
Chiara Pelliccia
Azienda Unità Sanitaria Locale Umbria 2
Author Profile
Raffaele La Porta
ASUR Marche
Author Profile
Antonio Vitiello
Azienda Unità Sanitaria Locale Umbria 1
Author Profile

Abstract

During the SARS-Cov-2 pandemic, it is essential to identify the risk factors that can cause a higher probability of infection and, therefore, worsen the patient's health. In fact, the known risk factors include already existing diseases and associated pharmacological treatments. A patient with multiple sclerosis takes immunomodulatory drugs and certainly has a high risk. Evidence and literature have shown that SARS-Cov-2 infection causes severe lung damage due to a poorly functioning immune system and overexpression of cytokines. Therefore the management of multiple sclerosis treatments in immunomodulating therapy must be carefully monitored. This article on the one hand analyzes and recalls the safety profile of all drugs for multiple sclerosis, on the other the recommendations adopted by different countries are highlighted, trying to understand if the suspension of MS treatment must actually materialize in order not to incur lethal covid pneumonia.