Stress cardiomyopathy (SC) is a syndrome characterized by transient
regional systolic dysfunction of the left ventricle (LV), in the absence
of obstructive coronary artery disease. Diagnosis of SC represents a
challenge as it is essentially a diagnosis of exclusion. We report the
case of a 21-year-old man who sustained mid-ventricular (MV) SC after a
seizure. Our case represents a combination of a predisposing acute
neuronal injury in a man that led to the development of an MV SC
variant, where cardiac MRI played an essential role in the diagnosis.