Side effect
The most common side effects of oral isotretinoin are dry mucous
membranes, dry skin, dry lip, dry eyes, and nose bleed (47). The most
important side effects are increased levels of total cholesterol, serum
triglycerides and liver enzymes (48). In women of childbearing age, oral
contraceptives should be used during and for one month after therapy to
avoid pregnancy because of the teratogenicity effect of oral
Isotretinoin (49).