Retinoids
Retinoidscontrol the formation of microcomedones, decrease the formation of
lesions and existing comedones, decrease sebum production and normalize
keratinization. Moreover, they may also demonstrate anti-inflammatory
properties (65, 66). Different topical preparations are available such
as creams, gels, foams, solutions, and lotions in a wide range of
concentrations (67). Topical retinoids are associated with skin dryness,
erythema, and pain, and may exacerbate dermatitis or eczema (67). Daily
sunscreen use is recommended due to increased sun-sensitivity and is
best used in the evening (68). Limited use of topical retinoids during
pregnancy because of the known teratogenic effect of similar oral
retinoids (69).