2.3 Definitions
Procedure-related ischemic complication was defined as any ischemic stroke or transient ischemic attack (TIA) which occurred within 30 days post-RFCA. Immediate procedure-related ischemic complication was defined as ischemic stroke or TIA within 3 days post-RFCA.
Ischemic stroke was defined as any neurologic symptom that persisted for more than 24 hours which could not be explained by other medical conditions. Transient ischemic attack was defined as any neurologic symptom that was not attributable to other medical cause, but resolved completely within 24 hours. If acute infarction was observed on brain CT or MRI, the event was classified as ischemic stroke despite complete restoration of neurologic symptoms. Neurologists confirmed the final diagnosis of ischemic stroke and TIA. Neurologic consequence of procedure-related stroke was classified into three stages: (i) None: no neurologic symptoms; (ii) Minimal: permanent neurologic symptoms which does not limit normal daily life; (ii) Significant: permanent neurologic symptoms which have significant limitation on normal daily life or occupation.