Importance:
The deleterious impact of smoking on the respiratory tract is well
known, however the relationship between smoking and chronic
rhinosinusitis (CRS) has not been well characterised.
Objective: We sought to analyse whether active smoking was a
risk factor for CRS and whether it has an impact on disease specific
quality of life.
Design: Sub-analysis of the Chronic Rhinosinusitis Epidemiology
Study (CRES), a prospective, questionnaire-based case-control study
conducted between October 2007 and September 2013.
Setting: Multicentre Case -Controlled across thirty UK
Tertiary/ Secondary care sites.