3.2 Detection of DRPs
As shown in Table 2, a total of 525 DRPs were identified during the study period. An average of 2.15 DRPs per patient was detected. Treatment effectiveness P1 (53.71%) was the most common problems of DRPs followed by treatment safety (33.90%). The main causes of DRPs were related to drug selection (71.43%) and dose selection (20.57%). These identified DRPs led to interventions proposed to prescribers in 96.19% of the cases. The most frequently recommended intervention was changing the drug (48.76%), followed by changing the dosage (24.76%) and starting a drug (11.62%). These interventions were accepted by the patients in 92.38% of the cases and were completely implemented in 90.48%.
The univariate analysis showed that the “number of drugs” and “number of chronic conditions” were the significant factors affecting the number of DRPs. In the multivariate analysis, only “number of drugs” was associated with the number of DRPs (P <0.0001), as described in Table 3.