<div>We are thankful for the valuable comments of Dr Ito on our article (1).
First of all, the age of the patients in the groups are homogeneous, not
statistically different. We found high procalcitonin levels only in
patients with prostate cancer, C-reactive protein was not different
between the groups. This point was shown in Table-1.</div><div>It is well known that chronic diseases are associated with elevated
C-reactive protein levels and not with procalcitonin levels. Finally, I
agree with Dr. Ito that the level of procalcitonin levels in cancer
group must be evaluated, but in our series the proportion of radical
treatment is very low; so only comparision of the Gleason scores will
not be objective. Further studies including high number of patients are
needed to define the relationship between inflammatory markers and
prostate cancer.</div><div>Best regards</div><div>REFERENCE</div><div>Ilktac A, Kalkan S, Caliskan S. C-reactive protein and procalcitonin
levels in prostate cancer. Int J Clin Pract. 2021;75:e13935.</div>