Umifenovir
Umifenovir, an indole-based, hydrophobic, dual-acting active antiviral / host-targeting agent, used for influenza and other respiratory infections treatment and prophylaxis. The ability of Umifenovir to exert antiviral effects across several mechanisms has led to extensive work into its use for a number of enveloped and non-enveloped RNA and DNA viruses, including Flavivirus, Zika virus, Foot-and-mouth disease, Lassa virus, Ebola virus, Herpes simplex, Hepatitis B and C virus, Chikungunya virus, Reovirus, Hantaan virus and Coxsackie virus B5 [38]. Umifenovir is currently being investigated in conjunction with currently available and investigational HIV therapies as a potential treatment and prophylactic agent for COVID-19 caused by SARS-CoV2 infections [37].