Conclusion
Based on our results, it is thought that some inflammatory diseases such
as suppurative rhinitis, acute otitis media, parotiditis, and
gastroenteritis are mediated by the defects occurred in A-T. Moreover,
our findings indicated that a pediatric patient with A-T, who one of his
relatives also had A-T, can have various manifestations of infections,
for example, pneumonia, chickenpox, zona, etc. In addition, HIgM
syndrome can be accompanied by A-T which may be appeared before other
manifestation. Among immune and hematological disorders, our patient
revealed neutropenia, HIgM syndrome, and thrombocytopenia. The nervous
system signs were ataxia and ocular nystagmus. Flow cytometry findings
showed that CD3+, CD4+ and CD8+ are more frequent, respectively.