Conclusion
This systematic review and meta-analysis summarized the available data
on the review question and identified an optimal protocol for FSE. With
short sectioning intervals perpendicular to the long axis of SLN
(L-protocol), FSE will yield high sensitivity in detecting metastases,
which allows for a precise intraoperative pathological assessment of
SLNs. This finding may redefine the role of FSE in SLNB and should be
considered in future practice of this technique.