In Silico analysis
Autodock vina 4.2 was used in the analysis of SBF-1 docking to the AR-DBD (PDB ID: 1R4I). Out of the many docking poses, only those possessing the highest docking score were chosen which gave a binding affinity at [-11.3 kcal/mol]. When we analyzed the predicted binding affinity, the large absolute value of the energy means the great affinity of corresponding ligand-receptor reaction as this datum represents the free energy of binding in AutoDock Vina v4.2 docking software.