Stone expulsion time (SET)
Compared to placebo only TADplusSILO, NIF-S, AL, SILO, TAD and TAM were more effective (Figure 3). Standard Mean differences (SMD) for stone expulsion time compared to placebo were best for TADplusSILO (SMD -2.8 (-4.3, -1.2) followed by NIF-S (SMD -2.0 (-3.2, -0.8) and SILO (SMD -1.4 (-2.1, -0.6) (Supplementary Table 3). SUCRA values obtained for time to stone expulsion estimate revealed highest values for TADplusSILO and least for NAF-S. (Supplementary Table 4 and Supplementary figure 4). Global test for inconsistency and node splitting approach did not reveal inconsistency in any comparisons. Loop specific approach revealed inconsistency in AL-C-NIF and SILO-TADplusSILO-TAM loops (Supplementary figure 5).