Conclusion
In this network meta-analysis of 50 studies with 14 drug treatment
groups for stone expulsion rate we noted naftopidil plus steroid to be
the best and nifedipine the worst. For individual drug comparison we
noted naftopidil followed by silodosin was the best and nifedipine the
worst. For secondary outcome stone expulsion time, tadalafil plus
silodosin was the best and naftopidil plus steroids the worst. From
individual drug comparison we noted silodosin to be best and naftopidil
worst. Considering both the efficacy parameters Silodosin appears to the
best individual treatment modality with best expulsion time and second
best expulsion rate for lower ureter stones less than 10 mm.