Subgroup analysis
We also performed subgroup analysis to test the efficacy of individual
drug treatments i.e AL, NAF, NIF, SIL, SILO, TAD, TAM. For SER there
were 43 studies for these 7 comparisons and highest sucra values were
obtained for NAF followed by SILO and TAD and least for NIF. For similar
group, for SET with 27 studies and 7 comparisons, highest sucra values
were obtained for SILO followed by SIL and TAD and least for NAF
(supplementary table 5 and 6).
We also plotted cluster ranking plots for this network analysis
presenting jointly the relative ranking of treatments (based on SUCRA
percentages) for SER and SET (Figure 4A). Treatments occupying the upper
right corner of this plot perform well for both the outcomes. Such as
tadalafil and silodosin combination for the whole network and silodosin
for the individual drug treatment analysis. (Figure 4A and 4B)