Conclusion
In this network meta-analysis of 50 studies with 14 drug treatment groups for stone expulsion rate we noted naftopidil plus steroid to be the best and nifedipine the worst. For individual drug comparison we noted naftopidil followed by silodosin was the best and nifedipine the worst. For secondary outcome stone expulsion time, tadalafil plus silodosin was the best and naftopidil plus steroids the worst. From individual drug comparison we noted silodosin to be best and naftopidil worst. Considering both the efficacy parameters Silodosin appears to the best individual treatment modality with best expulsion time and second best expulsion rate for lower ureter stones less than 10 mm.