Xin Su

and 15 more

Background: Atrial fibrillation (AF) is common in abdominal solid organ transplant recipients and a cause of morbidity and mortality in this population. However, the outcomes of catheter ablation (CA) in transplant recipients with AF remain unclear. This study aimed to elucidate the outcomes of CA in renal and hepatic transplant recipients. Methods and Results: Between 2015 and 2019, 14 transplant recipients (9 with kidney transplantation and 5 with liver transplantation) were enrolled from among 10,741 AF patients and underwent CA at Anzhen Hospital. Another 56 patients matched by age, sex and AF type were selected as the control group (4 controls for each transplant recipient). During a mean follow-up of 30.0±13.3 months after the initial procedure, 10 (71.4%) of the transplant patients, compared to 41 (73.2%) of the control patients, remained free from AF recurrence(P=1.000). A repeated procedure was performed in 1 transplant patient and in 6 control subjects. Consequently, 11 (78.6%) of the transplant patients, compared to 46 (82.1%) of controls, were in sinus rhythm after the repeated ablation (P=0.715). Notably, Kaplan–Meier analysis did not demonstrate any significant differences in the atrial arrhythmia-free rate after the initial and repeated procedure between the two groups. Vascular complications were identified in 1 transplant patient and 2 control subjects, while no life-threatening complications were observed in either group. There was no transient allograft dysfunction in transplant recipients after CA. Conclusion: CA is safe and effective in abdominal solid transplant recipients, and may be an optimal therapeutic strategy for this group.

Wei Wei

and 13 more

Background Nodo-ventricular(NV) fiber-related reentrant tachycardias are so rare that most of them were reported by case, while few reports have summarized their common and individual features. Objectives To clarify the electrophysiological mechanism of supra-ventricular tachycardias (SVT) related to concealed NV fibers. Methods and Results We studied the intra-cardiac electrograms during electrophysiological study of 3 cases of SVT concerning concealed NV fibers. Maneuvers including ventricular entrainments, His bundle refractory period ventricular stimuli, adenosine triphosphate injection and so on were done for differential diagnosis before ablation. Among these patients, one had AVNRT with a bystander NV fiber, the other 2 had NV fiber-mediated orthodromic reentrant tachycardias (NVRT). VA dissociation were observed during SVT in all with antegrade His bundle conduction sequence. His bundle refractory period ventricular stimuli reset tachycardias with resetting of the H-H interval advancing the V-V interval, suggesting the existence of an accessory pathway. The cycle length of an NVRT prolonged during the status of functional right bundle branch block. Multiple QRS fusion morphologies during ventricular entrainments on a fixed site could be observed. Conclusions Concealed NV fibers can mediate orthodromic SVT or be a bystander of AVNRT. V-A dissociation usually occur during such SVTs. An NV fiber not only expresses the characteristics of an AP, but also the characteristics of the AV node. Multiple QRS fusion morphologies during ventricular entrainments or His bundle refractory period ventricular stimuli on a fixed site can discriminate NV fibers from NF fibers.