Correlation of HPV with inverted papilloma with malignant
transformation.
From this study, three out of 44 patients had IP with synchronous SCC.
They were classified into the group IP with SCC (Table 1). During this
study period, no patients had metachronous SCC. Two out of these three
patients had positive HPV results. Both HPV 16 and 18 were detected in
the two patients.
Our results showed an association between HPV 16 and 18 infection with
malignant transformation (p<0.05). The HPV 16 infection and
malignant transformation was statistically significant with a p value of
0.013 while HPV 18 infection and malignant transformation showed a p
value of 0.003 (Table 1).