SD: Standard deviation, n: Number, BSA: body surface area
In comparison between hyperthyroid and control groups, there was no significant difference in clinical parameters such as age, sex, and body surface area (BSA), and two groups were matched. Hemodynamic parameters assessment showed that, the hyperthyroid patients had a higher heart rate compared to control group at rest, but both systolic and diastolic blood pressures were not significantly different between the two groups. All the subjects were in sinus rhythm without any significant ST segment deviation.
In echocardiographic evaluation of diastolic function, we found that, no patient had septal e’<7 or lateral e’<10cm/s and mean values were 9.74±2.1 and 13.43±2.9, respectively. Mean E/e’ at rest in the hyperthyroid patients was 7.2 ±1.1 that was in normal range and also was not elevated in none of the individuals. Also, TR velocity and LAVI met criteria for diastolic dysfunction in no patient; so, regarding the ASE guideline definition, no one had diastolic dysfunction at rest. (Table-2)
Diastolic indices including septal and lateral mitral annular velocities, TR velocity, E/e’ ratio, LAVI, MPI, and PAP showed no notable difference between the two groups; IVRT was the only parameter that was lower in the hyperthyroid patients compared to the control group. (P value: 0.008; Table-2)
Table -2. Comparison of clinical characteristic, hemodynamic, and echocardiographic parameters at rest between the hyperthyroid and control groups