Analysis of the fold change of T, NK and NKT cell count in lung cancer patients compared to CTRL from before to after culture
The fold change in the CD3, CD4, CD8, and NKT populations showed greatly increased in a patient group before chemotherapy when compared to CTRL while showing a less significant increase in the during and after induction of chemotherapy patient groups. Then again, NK and NKCD8 fold change percentages were not markedly changed in lung cancer patients before and during induction of chemotherapy compared to CTRL, yet they displayed a significant decrease after induction of chemotherapy. Moreover, NKCD4 cells showed a considerable increase in the fold change percentage in lung cancer patients before induction of chemotherapy and in contrast, a significant decrease was noted in patients after induction of chemotherapy when compared to the CTRL group fig 3A.