Analysis of the fold change of granzyme B expression on T, NK
and NKT cells in lung cancer patients compared to CTRL from before to
after culture
when analyzing results in terms of fold changes of GzB expression on
CD3, CD4, CD8, NK, NKT, NKCD4 and NKCD8 cells in lung cancer patients
and CTRL before culture with after culture, all cell populations except
the NK cells showed a marked increase in their expression levels of GzB
upon activation in the newly diagnosed non-treated lung cancer group of
patients. Similarly, these CD3, CD4, CD8, NKT, NKCD4 and NKCD8 cells all
demonstrated a significant fold reduction during and after induction of
chemotherapy when compared to CTRL. However, NK cell population where
shown to be almost indifferent to the activation conditions, exhibiting
no significant discrepancy in their fold change when compared to the
CTRL fig 3B.