Analysis of cytokines, chemokine’s and interleukins profiles of
plasma of patients compared to CTRL
Several cytokines and chemokines were measured from healthy, before,
during and after induction of chemotherapy lung cancer patients, CXCL8
shows a highly significant increase in lung cancer patients before
induction of chemotherapy while slightly increase were shown in lung
cancer patients during and after induction of chemotherapy when compared
to healthy CTRL. Interestingly, IL-6 and IL-1 and shows a highly
significant increase in lung cancer patients before and during induction
of chemotherapy (100 and 13000 fold increase respectively) and no
significant change in patients after induction of chemotherapy when
compared to CTRL. According to CCL2, there is a highly significant
increase in lung cancer patients before (250 fold) during and after
induction of chemotherapy when compared to CTRL. CXCL10 shows a highly
significant increase in lung cancer patients before and during the
induction of chemotherapy when compared to CTRL. On the other hand IL-5,
CCL11 and CCL4 show no significant change in their percentages in any
group compared to the CTRL group fig 4.