|
Nx
(n = 11)
|
Nx+4091
(n = 6)
|
Hx
(n = 9)
|
Hx+4091
(n = 11)
|
Hx+SU
(n = 7)
|
Hx+Su+4091
(n = 6)
|
BW (g) |
23 ± 3 |
26 ± 5 |
24 ± 3 |
23 ± 3 |
25 ± 3 |
26 ±
2 |
HR (bpm) |
455 ± 71 |
508 ± 71 |
455 ± 36 |
466 ± 34 |
519 ± 19 |
408 ± 52¶¶
|
LVSP (mmHg) |
104 ± 11 |
96 ± 4 |
105 ± 6 |
97 ± 4 |
102 ± 21 |
98 ± 5 |
LVEDP (mmHg) |
11 ± 3 |
6 ± 3 |
15 ± 3 |
11 ± 2 |
17 ± 10 |
8 ±
2 |
LVESV (uL) |
40 ± 9 |
46 ± 11 |
35± 8 |
37± 11 |
42 ± 15 |
37 ±
12 |
LVEDV (uL) |
55 ± 10 |
68± 10* |
50 ± 9 |
58 ± 12 |
51 ± 13 |
57 ± 11 |
CI (mL/m2/min) |
1092 ± 270 |
1495±142** |
850 ± 138* |
1413 ±
303§§§
|
703 ± 76** |
990 ±
208¶
|
Ea (mmHg/uL) |
5.6 ± 1.0 |
3.8 ± 0.4*** |
7.2 ± 1.0* |
4.3 ±
0.9§§§
|
9.2 ± 1.5***§
|
4.5 ±
0.5¶¶¶
|
dP/dtmax (mmHg/s) |
5841 ± 803 |
6385 ± 462 |
5559 ± 496 |
5567 ± 668 |
6021 ± 1114 |
5510 ± 1302 |
-dP/dtmin (mmHg/s) |
5266±1029 |
5890 ± 570 |
4945 ± 788 |
4753 ± 553 |
4648 ± 1099 |
4504 ± 1302 |
dP/dVmax (mmHg/uL) |
8.5 ± 2.8 |
6.5 ± 1.6 |
8.7 ± 2.8 |
6.1 ± 2.2§
|
15.7 ±
4.2**§§
|
7.0 ± 1.7¶¶
|
Tau (ms) |
12 ± 4 |
8 ± 2* |
13 ± 4 |
11 ± 3 |
12 ± 2 |
10 ±
2 |
Fulton’s index, RV/LV+S |
0.23 ± 0.04 |
0.25 ± 0.04 |
0.39±0.08*** |
0.20±0.03§§§
|
0.39±0.03*** |
0.29±
0.03¶¶¶
|
Ht (%) |
46 ± 3 |
44 ± 2 |
60 ± 3*** |
48 ±
6§§§
|
59 ± 3*** |
56 ± 4 |