Enzyme |
Conversion process |
Strategy |
Substrate |
L-PA production |
Conversion |
Productivity |
Ref |
rAIP + dpkA
|
Purified enzyme
|
Racemic catalysis
|
L-lysine 400mM
|
45.1 g/L
|
87.5 %
|
0.98 g/L/h
|
Y. Tani et al
(2015)
|
rAIP + dpkA
|
Fermentation
|
Fed-batch
|
Lysine-HCl solution
|
46.7 g/L
|
-
|
2.41 g/L/h
|
J. Cheng et al
(2018)
|
LCD
|
Whole cell
|
Recycling
|
L-lysine 170mM
|
17.25 g/L
|
77.7 %
|
0.36 g/L/h
|
H. Ying et al
(2015)
|
LCD
|
Whole cell
|
Mutagenesis & Fed-batch
|
L-lysine 820mM
|
73.4 g/L
|
55.3 %
|
0.83 g/L/h
|
H. Ying et al
(2018)
|
LCD |
Whole cell |
Reinforced enzyme |
Lysine-HCl 1M |
93.5 g/L |
72.4 % |
0.78 g/L/h |
In this study |