3.4. Cellular and Humoral Systemic Immune Response
Figure 3 shows the cellular systemic immune response between non-asthmatic and asthmatic children, which has been evaluated by the whole blood analysis. Asthmatic children demonstrated increased density of lymphocytes (Figure 3D; p<0.02 and 3E; p<0.003), monocytes (Figure 3F; p<0.002 and 3G; p<0.001), eosinophils (Figure 3H; p<0.008 and 3I; p<0.04) and basophils (Figure 3J; p<0.04 and 3K; p<0.01).
Figure 4 shows the humoral systemic immune response between non-asthmatic and asthmatic children, which has been evaluated by humoral mediators’ measurement in the blood serum. The results showed increased levels of GM-CSF (Figure 4A; p<0.0001), TGF-beta (4B; p<0.004), IL-4 (Figure 4C; p<0.0002), IL-5 (Figure 4D; p<0.01) in asthmatic children as compared with non-asthmatic children, while for TSLP no differences were found (p>0.05).