Contribution to authorship
RKM, FLM and MDK performed the previous systematic reviews and designed the study, with MKn. All authors were involved in analysing and interpreting the data led by AT. FLM drafted the first manuscript, and all authors amended and approved the manuscript.
Details of ethical approval: This study has ethical approval from the North London REC1 (REC Ref. Number: 10/H0717/20) awarded 13th April 2016.
Funding : The study is funded by the British Maternal Fetal Medicine Society (BMFMS) and Twins Trust.