(n=521-1039d) (n=85-160d) p-value f) (n=88-147d) p-valuef) (n=21-35d) p-valuef) p-value f) p-valuef)
BMI (kg/m2) 14 yr 18.7 (17.4; 20.2) 19.2 (17.9; 20.9) .011 19.3 (18.0; 20.6) .006 20.4 (18.6; 22.8) <.001 .022 .018
BMI (kg/m2) 31 yr 22.6 (20.7; 24.9) 24.0 (21.8; 26.7) <.001 24.1 (21.5; 27.2) <.001 28.0 (22.4; 33.9) <.001 .001 <.001
BMI (kg/m2) 46 yr 25.2 (22.6; 28.6) 26.9 (23.9; 30.5) <.001 26.2 (23.7; 30.3) .002 31.4 (26.1; 37.3) <.001t <.001t.003t
Waist (cm) 31 yr 76.0 (70.0; 83.0) 78.0 (72.5; 85.3) .005 81.0 (71.0; 92.0) <.001 83.5 (75.0; 98.0) <.001 .113 .021
Waist (cm) 46 yr 83.5 (77.0; 93.5) 90.0 (79.5; 99.0) <.001 86.5 (79.5; 97.8) .020 94.5 (83.6; 115.1) .001t.003t .011t
Change in BMI (kg/m2) 14-31 yr 3.83 (2.27; 5.74) 4.89 (3.21; 7.57) <.001 4.59 (2.40; 7.54) .009 5.94 (3.69; 11.1) <.001 .015 .033
Change in BMI (kg/m2) 31-46 yr 2.40 (0.81; 4.19) 2.65 (0.97; 5.61) .068 2.19 (0.71; 4.60) .745 2.96 (0.14; 4.40) .895 .801 .479
Change in BMI (kg/m2) 14-46 yr 6.33 (3.90; 9.33) 7.54 (5.32; 11.62) <.001 7.21 (4.16; 10.5) .151 9.82 (6.23; 14.6) <.001t .001t.073t
Change in waist (cm) 31-46 yr 8.30 (2.60; 14.0) 8.80 (3.00; 16.0) .352 8.00 (3.00; 15.0) .692 11.0 (5.00; 19.9) .203t.247t .691t
Total testosterone (nmol/l) 31 yr 1.80 (1.40; 2.30) 1.90 (1.40; 2.40) .527 (.979) 2.00 (1.70; 2.80) <.001 (.003) 2.60 (1.95; 3.10) .002t (.083) .284t (.558) .011t (.061)
FAI 31 yr 3.75 (2.57; 5.44) 4.41 (2.67; 6.00) .097 (.985) 5.08 (3.14; 7.64) .002 (.372) 10.31 (4.55; 13.31) .001t (.013) .015t (.189) .002t (.012)
Total testosterone (nmol/l) 46 yr 0.82 (0.62; 1.05) 0.80 (0.61; 1.07) .963 (.664) 0.86 (0.68; 1.05) .277 (.236) 0.97 (0.72; 1.13) .092t (.066) .315t (.232) .113t (.063)
FAI 46 yr 1.53 (1.06; 2.22) 1.63 (1.17; 2.24) .324 (.727) 1.62 (1.29; 2.25) .064 (.347) 2.17 (1.43; 3.41) .001 (.037) .020 (.176) .007 (.037)
Data is expressed as medians (interquartile ranges). The significance test used was Mann-Whitney U test, when a rule |skewness/standard error of skewness|>1.96 was valid for the dependent variable, otherwise t-test was used (t-sign).aP-value: non-PCOS with HDP compared to non-PCOS without HDP. bP-value: srPCOS without HDP compared to non-PCOS without HDP. cP-value: srPCOS with HDP compared to non-PCOS without HDP. dP-value srPCOS with HDP compared to srPCOS without HDP. eP-value: srPCOS with HDP compared to non-PCOS with HDP. fThe numbers of women in separate analyses varies due to non-response to some items. fThe results were adjusted for BMI at age 31 and 46 years using univariate general linear modelling (ANCOVA). BMI: body mass index; FAI: free androgen index; HDP: hypertensive disorder of pregnancy; srPCOS: self-reported polycystic ovary syndrome; SHBG: sex hormone binding globulin.