Abbreviations : 2-DG: 2-deoxy-D-glucose; ADMETox: Adsorption, Distribution, Metabolism, Toxicity; CoV: Coronavirus; DARS: Decoys as Reference State; FFT: Fast Fourier Transform; GPCR: G-protein coupled receptor; MERS: Middle East Respiratory Syndrome; NSP: Non structural protein; O.E.C.D.: Organisation for Economic Co-operation and Development; PDB: Protein Data Bank; QSAR: Quantitative Structure Activity Relationship; RCSB: Royal Collaborative Structural Biology; SARS: Severe Acute Respiratory Syndrome; T.E.S.T.: Toxicity Estimation Software Tool; TPSA: Total polar surface area; VIF: Viral infectivity factor