AUTHOR CONTRIBUTIONS
SK, SM, and KO: designed the work; YS, JK, AN, HTaka, KK, HTake:
generated the biological samples; YS, TO, NM, SG: performed the
experiments; YS, SK, SM, KO: acquired, analyzed, and interpreted the
data; YS and SK: wrote the manuscript; SM and KO: revised and approved
the final version of the manuscript.