Fig. 2. PP242 treatment showed tumor growth inhibition in vivo. (A)
Tumor growth (in the right flank region) rate of LS174T cells induced
colon cancer xenograft model after treating with vehicle (xenograft
control) and PP242 (PP242 treated; 60
mg.kg-1.day-1) for three weeks.
Treatment was started when the tumor sized reached 150 ~
200 mm³. Tumor volume was presented as mean ± SD. (B) Representative
images of tumor weight of xenograft control (vehicle) and PP242 treated.
(C) Mean weight of harvested tumor after the three weeks treatment of
PP242. *p<0.05; **p<0.01; ***p<0.001; (n=5
per group).