Christiansen et al [33]
|
Netherlands
(2005)
|
Prospective cohort
|
474 patients with a firts VTE
|
7.3 years
|
HR=1.4 ; IC= 0.9-2.2
HR=1.6 IC=1-2.7†
|
Santamaria et al [21]
|
Italy
(2005)
|
Randomized mulicentric prospective study
|
195 patients with first proximal unprovoked VTE
|
46,8 months
|
HR=1.78, p=0.046 ‡
|
Douketis et al [24]
|
Canada
(2010)
|
Meta-analysis of 7 prospective studies
|
1818 patients with first unprovoked VTE
|
26.9 months
|
HR=1 ; p=1
|
Kudo et al [34]
|
Australia
(2016)
|
Retrospective multicentric study
|
152 patients with an index VTE
|
1 year
|
Patients with recurrent VTE had a higher rate of positive thrombophilia
results (52% vs 27% (p=0.007)
|
Lim et al [13]
|
Australia
(2017)
|
Retrospective study
|
742 patients with an index VTE
|
27 months
|
HR= 1.19 ;p= 0.74
|
Satpanich and Rojnuckarin [22]
|
Thai
(2018)
|
Retrospective cohort
|
198 patients with an index VTE
|
52 months
|
HR= 3.52 ; p = 0.01 ‡
|