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\begin{document}

\title{Ultrasonographic diagnosis of rare primary cervical cancer and common
cervical cancer}



\author[1]{jiaoling li}%
\author[2]{Congmin Gu}%
\author[2]{Haiqing Zheng}%
\author[1]{xiaofang liu}%
\author[1]{xiuping geng}%
\author[2]{Haiying Wu}%
\affil[1]{Affiliation not available}%
\affil[2]{Guangzhou Women and Children’s Medical Center, Guangzhou Medical University}%


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  \date{May 07, 2024}


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\begin{abstract}
OBJECTIVES: To summarize ultrasonographic features of rare primary and
common cervical cancer and the association of these cancers with HPV
infection so as to diagnose rare primary cervical cancer. METHODS:
Sixty-five cases with cervical cancer suspected by ultrasonography and
three cases with clinical symptoms treated at our department~underwent
cervical biopsy. Sixty-four diagnosed cases were retrospectively
analyzed and divided into common-type (CTCC) and rare-type (RTCC)
cervical cancers. RESULTS: Sixty-one cases were diagnosed, four
misdiagnosed, three missed the diagnosis by ultrasonography, the
sensitivity of which was 95.31\% (61/64). The common-type cervical
cancer had 43 cases of squamous cell carcinoma. The rare-type cervical
cancer had 15 cases of adenocarcinoma, four of small-cell carcinoma, and
two of adenosquamous carcinoma. The demographic characteristics of the
two groups were not significantly different (P \textgreater{} 0.2). The
tumor size in RTCC were smaller than those in CTCC (P \textless{} 0.05).
Hypoechoic lesions in CTCC and isoechoic lesions in RTCC composed
74.42\% (32/43) and 61.90\% (13/21), respectively (P \textless{} 0.001).
Exophytic in CTCC and endophytic in RTCC composed 67.44\% (29/43) and
66.67\% (14/21), respectively (P = 0.01). HPV infection composed 83.72\%
(36/43) in CTCC and 47.62\% (10/21) in RTCC, respectively (P = 0.003).
Color Doppler blood signals were found in all cases, as compared with
normal cervical tissue.~The consistency between ultrasonography and
pathology staging diagnosis of RTCC was good (Weighted kappa (95\%CI) =
0.87). CONCLUSION: Ultrasonography can distinguish RTCC from CTCC. There
is a very good consistency between ultrasonography and pathology staging
diagnosis of RTCC.%
\end{abstract}%



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