2.3 ROSE
Biopsy specimens were expressed onto labeled glass slides and smearing
was performed by an on-site cytotechnologist. Rapid staining was
performed using Diff-Quik stain. Cytologic glass slides were then
evaluated under light microscopy by the cytotechnologists for immediate
interpretation of whether the sample was sufficient for a provisional
diagnosis as well as for all later laboratory requirements. A quick
feedback was sent back to the bronchoscopist by cytotechnologists. The
bronchoscopist terminated or modified the sampling process based on the
information. If sufficient specimens were obtained and diagnostic
objective had been met from imprint cytology, sampling was stopped,
conversely, but otherwise, sampling was continued with the appropriate
adjustment.