Coronavirus Disease 2019 (COVID-19) is an emerging disease with a rapid increase in cases and deaths since its first identification in Wuhan, China, in December 2019. As of March 21, 2020, more than 193,327 confirmed cases of COVID-19 have been reported in 178 countries and states, and Italy is currently the country with the highest number of confirmed casesoutside of China. The WHO declared a public health emergency of international concern (PHEIC) on January 30, 2020, and characterised the COVID-19 situation as a pandemic on March 11, 2020, in response to the human-to-human transmission and rapid growth of the outbreak. The popularity of COVID-19 has obviously entered a new stage and has spread rapidly in countries outside China. As the front-line clinical workers, Obstetricians and Gynaecologists should be vigilant to assess whether pregnant women or female patients are suspected or confirmed of infection, improve their knowledge of prevention and treatment of COVID-19, and take effective precautionary measures.Here, we reviewed the current understanding of COVID-19, combined with the particularity of the patients in gynecology and obstetrics, and share our experience of current clinical practice recommendations and precautions taken at frontline, and discuss how obstetricians and gynaecologists should prepare themselves to deal with the outbreak of this disease.