Statistical analysis
Continuous variables were expressed as mean and standard deviation for
normally distributed data and median and inter-quartile range for skewed
data. Categorical variables were expressed as counts and percentages.
Chi-square tests with
Bonferroni
post hoc were used to compare proportions among categorical variables.
Mann–Whitney U tests were used to analyze the non-normal distribution
variables. Binary logistic regression was conducted to analyze the
association with adverse fetal outcomes (combining induced abortions,
SFLs, preterm births, and MCMs) using pregnancy planning, age at
conception, appropriate folic acid supplementation, whether taking VPA
during pregnancy, and GTCS frequency during pregnancy as covariates.
Two-tailed P values < 0.05 were considered
statistically significant. In the post hoc of the chi-square test,P boundary value (α’) was adjusted according to the Bonferroni
method. Statistical analysis was performed using SPSS 24.0 (IBM Inc.).