Conclusions
In conclusion, our study investigated the clinical characteristics and
fetal outcomes of WWE in planned and unplanned pregnancy. We found that
WWE with a planned pregnancy were associated with more optimized AED
treatment patterns, better seizure control, more appropriate folic acid
supplementation, and less fetal MCMs. Our study further verified the
necessity and importance of pregnancy planning in the effective
management of WWE of childbearing age. Further research with a larger
sample size and comprehensive information on neonatal outcomes is
necessary.
Acknowledgements: None.
Disclosure of Interests: None of the authors has any conflict
of interest to disclose.
Contribution to authorship: YYZ had full access to all of the
data in the study, conceived and designed the study, analysed and
interpreted the data and drafted the manuscript. YYZ and CGS both
contributed equally to the research study and manuscript. XW interpreted
the data and revised the article. WJ conceived and designed the study,
interpreted the data and revised the article. YLJ, JJZ, FY, XAY and FY
interpreted the data and revised the article. All authors approved the
final version.
Details of ethics approval: This study was approved by the
Ethics Committee of Xijing Hospital (KY20163380 -1).
Funding: This study was supported by the National Natural
Science Foundation of China (Grant Numbers 81771406 to Wen Jiang &
Grant Numbers 81974204 to Wen Jiang).