Bioinformatic tools (cut-off score)
Positive controls
Positive controls
Negative controls
Negative controls
Negative controls (secondary analysis)
Negative controls (secondary analysis)
Sensitivity
Specificity
Specificity (secondary analysis)
True Positive False Negative False Positive True Negative False Positive True Negative
ΔtESRseq ( < -0.75) 24 9 51 199 30 220 73% 80% 88%
ΔHZEI ( ≤ -5) 25 8 45 205 23 227 76% 82% 91%
HOT-SKIP (alt/wt > 1) 15 18 56 194 37 213 45% 78% 85%